Table 3.
Apparent Permeability Coefficients (×10−5 cm/s) of DEX, TRIAM, and E2β Across Human Sclera in Passive Transport, Anodal Iontophoresis, and Cathodal Iontophoresis Experiments*
| DEX | TRIAM | E2β | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Formulations | Passive | Cathodal | Anodal | Passive | Cathodal | Anodal | Passive | Cathodal | Anodal |
| Mixed micelles | 0.6 ± 0.1 | 1.4 ± 0.3 | 1.3 ± 0.2 | 0.24 ± 0.06 | 0.3 ± 0.1 | 0.7 ± 0.1 | 0.16 ± 0.04 | 0.7 ± 0.3 | 0.8 ± 0.2 |
| Control | 1.2 ± 0.6 | 1.2 ± 0.7 | 3.0 ± 1.5 | 1.0 ± 0.1 | 1.3 ± 0.2 | 4.0 ± 1.0 | 1.0 ± 0.2 | 1.2 ± 0.6 | 4.0 ± 1.7 |
Mean ± SD, n ≥ 3.