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. Author manuscript; available in PMC: 2013 Nov 3.
Published in final edited form as: Vascul Pharmacol. 2010 Mar 31;53(0):10.1016/j.vph.2010.03.005. doi: 10.1016/j.vph.2010.03.005

Figure 5. NADPH oxidase-dependent superoxide levels in the peripheral lung of Control and Shunt lambs.

Figure 5

NADPH oxidase-dependent Superoxide levels in peripheral lung tissue of Control and Shunt lambs at 2-, 4-, and 8-weeks of age were estimated using electron paramagnetic resonance (EPR). Developmentally there is a developmental increase in superoxide production in both the Control-(A) and Shunt-lambs (B). *P<0.05 vs. 2-weeks of age; †P<0.05 vs. 4-weeks of age. In addition compared to age matched Control lambs, there is a significant increase in NADPH oxidase dependent superoxide generation in Shunt lambs at 2-and 4-weeks (C & D) but no change at 8-weeks of age (E). Values are mean ± SD; n=6 control and n=6 shunt at each age. *P<0.05 vs. age matched Control lambs.