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EC50 and I-Ag7 binding of peptides derived from IAPP.
| Name | Peptide Sequence | EC50 (nM) | I-Ag7 binding (relative to HEL %) |
|---|---|---|---|
| KG38 | KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTYG | 0.2 | n.d.* |
| DS23 | DKRKCNTATCATQRLANFLVRSS | 55 | 93.5 |
| KS20 | KCNTATCATQRLANFLVRSS | 0.2 | 61.9 |
| KV17 | KCNTATCATQRLANFLV | 10 | 10.8 |
| KN14 | KCNTATCATQRLAN | > 105 | 44.1 |
| KQ10 | KCNTATCATQ | > 105 | 12.3 |
| CS19 | CNTATCATQRLANFLVRSS | 5 | 40.7 |
| NS18 | NTATCATQRLANFLVRSS | > 105 | 30.9 |
| TS17 | TATCATQRLANFLVRSS | > 105 | 36.8 |
n.d. : not determined
