Table 2.
Lifestyle and serological risk factors of gastric cancer
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| Cases n=52 (%) | Controls n=94(%) | OR (95%CI) | P | OR (95% CI) | P | |
|
| ||||||
| Smoking | ||||||
| Ever smoked | 14 (27) | 7 (7) | 4.6 (1.5–14.3) | 0.002 | 3.4 (1.0–11.4) | 0.047 |
| Current smoker | 9 (17) | 3 (3) | 6.3 (1.5–37.8) | 0.009 | - | - |
|
| ||||||
| Alcohol intake | ||||||
| Ever consumed alcohol regularly | 21 (40) | 17 (18) | 3.1 (1.3–7.1) | 0.005 | 2.8 (1.1–7.3) | 0.03 |
| Currently consumer of alcohol | 12 (23) | 9 (10) | 2.8 (1.0–8.2) | 0.046 | - | - |
|
| ||||||
| Family history | 1 | 1 | 1.000 | |||
|
| ||||||
| Serological evidence* of: | ||||||
| H. pylori infection | 41/51 (79) | 83/92 (88) | 0.4 (0.1–1.3) | 0.082 | - | - |
| CagA+ | 31/46 (67) | 26/82 (66) | 1.0 (0.5–2.5) | 1.000 | - | - |
| Low pepsinogen 1 | 7 (14) | 7 (8) | 1.8 (0.5–6.6) | 0.381 | - | - |
| Low pepsinogen 1:2 ratio | 29 (57) | 26 (30) | 3.0 (1.4–6.7) | 0.004 | 3.8 (1.7–8.6) | 0.002 |
| Low gastrin-17 | 4/51 (8) | 5.89 (7) | 1.4 (0.3–7.0) | 0.724 | 5.1 (1.1–7.3) | 0.04 |
*
Denominators as shown when data not available for all sera