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. 2010 Jun 24;3(4):362–369. doi: 10.1111/j.1751-7915.2010.00191.x

Table 3.

Genome (re‐)annotation pipelines.

Pipeline Organization Description Access/distribution Reference
IGS University of Maryland A FREE resource for genomics researchers and educators bringing advanced bioinformatics tools to the lab bench and the classroom http://ae.igs.umaryland.edu/cgi/index.cgi
Free service None
JCVI annotation service J. Craig Venter Institute (JCVI) Free to use genome annotation service http://www.jcvi.org/cms/research/projects/annotation‐service/overview/
Free to use annotation service None
MiGAP Database Center for Life Sciences (DBCLS) Microbial Genome Annotation Pipeline (MiGAP) for diverse users http://migap.lifesciencedb.jp/
Note: site is in Japanese http://www.jsbi.org/modules/journal1/index.php/GIW09/Poster/GIW09S001.pdf
MaGe/MicroScope GENOSCOPE Magnifying Genomes: microbial genome annotation system http://www.genoscope.cns.fr/agc/mage
Free service Vallenet et al. (2006); Vallenet et al. (2009)
BASys University of Alberta, Canada A web server for bacterial genome annotation http://wishart.biology.ualberta.ca/basys/
Free to use Van Domselaar et al. (2005)
RAST Fellowship for Integration of Genomes (FIG) The RAST Server: Rapid Annotations using Subsystems Technology based on the Seed http://rast.nmpdr.org/
Free to use service Aziz et al. (2008)
xBASE University of Birmingham, UK Bacterial genome annotation service http://xbase.ac.uk/annotation/
Free to use service Chaudhuri et al. (2008)
IMG ER Joint Genome Institute (JGI) A system for microbial genome annotation expert review and curation http://img.jgi.doe.gov/er
Free service Markowitz et al. (2009)
GenVar Virginia Bioinformatics Institute Bacterial gene annotation and comparative genomics pipeline http://patric.vbi.vt.edu/downloads/software/GenVar
Free for non‐commercial use Yu et al. (2007)
Pedant‐Pro Biomax Genome analysis package for comprehensive analysis of DNA and protein sequences http://www.biomax.de/products/pedantpro.php
Commercial license Frishman et al. (2001)
AGMIAL INRA, France An annotation strategy for prokaryote genomes as a distributed system http://genome.jouy.inra.fr/agmial/
Open source license Bryson et al. (2006)
GenDB CeBiTec, Germany Bacterial annotation system http://www.cebitec.uni‐bielefeld.de/groups/brf/software/gendb_info/
Free to use, stand‐alone software Meyer et al. (2003)
DIYA DIY Genomics Consortium A bacterial annotation pipeline for any genomics lab https://sourceforge.net/projects/diyg/
Free to use, stand‐alone software Stewart et al. (2009)
SABIA LNCC, Brazil Bacterial annotation system http://www.sabia.lncc.br/
Free to use, stand‐alone software Almeida et al. (2004)
MAGPIE Genome Prairie Project, Canada Genome annotation system http://magpie.ucalgary.ca/
Free to use, stand‐alone software Gaasterland and Sensen (1996)
Restauro‐G Institute for Advanced Biosciences, Keio University A Rapid Genome Re‐Annotation System for Comparative Genomics http://restauro‐g.iab.keio.ac.jp/
Software distributed under the GNU public license Tamaki et al. (2007)
ATUCG system Universidade Federal do Rio Grande do Sul, Brasil Agent‐based environment for automatic annotation of Genomes None
Software should be requested at authors Nascimento and Bazzan (2005)
Taverna: annotation of genomes University of Manchester Interactive genome annotation pipeline. http://www.taverna.org.uk/introduction/taverna‐in‐use/annotation/annotation‐of‐genomes/ Hull et al. (2006)
KAAS Kyoto Encyclopedia for Genes and Genomes (KEGG) KEGG automated annotation service for metabolic pathways http://www.genome.jp/tools/kaas/
Free to use service Moriya et al. (2007)