Schematic illustration conveying the notion that aspects of socioeconomic position (SEP) over the lifecourse can come to affect health and disease states via neurobiological pathways. Affective, cognitive, behavioral, and physiological factors linking different dimensions of SEP to health and disease states can be viewed as bidirectionally related to multiple brain networks, amenable to study by neuroimaging approaches. The links between dimensions of SEP and the function and structure of different brain networks can be further conceptualized as subject to effect modification and mediation by environmental, social, and individual level factors that can influence downstream pathways to health and disease.