Table 4.
Factor | Cost-effectiveness ratio ($/QALY gained) |
---|---|
Base case analysis |
3,016 |
Simulation model |
|
Log-normal |
2,874 |
Weibull |
3,341 |
Recurrence rate (95% CI: 30.5% - 38.8%) |
2,446 ‒ 3,891 |
Utility |
|
Remission after surgery (95% CI: 0.788 - 0.898) |
2,825 ‒ 3,231 |
Metastasis (95% CI: 0.231 - 0.473) |
2,998 ‒ 3,032 |
QALY gained (95% CI: 0.48 – 1.96) |
1,901 ‒ 7,696 |
Recurrence cost (95% CI: $2,032 - $2,422) |
2,834 ‒ 3,149 |
End of life cost (95% CI: $3,997 - $4,766) |
2,682 ‒ 3,302 |
Exclusion of end-of-life costs due to gastric cancer |
3,677 |
S-1 cost (95% CI: $4,322 - $4,772) |
2,810 ‒ 3,173 |
Total cost difference (95% CI: $2,911 - $4,512 ) | 2,347 ‒ 3,638 |
Discount rate: 3% for both cost and effectiveness, Period: lifetime.