Figure 6.

Deregulation of miRNA machinery affects miRNA processing in DLBCLs (cohort 1). (a) Histograms show a significantly higher miRNA processing efficiency for both miR-155 and miR-146a in de novo DLBCLs as compared with transformed DLBCLs and LNs. (b) The levels of pri-miRNA transcripts do not show any significant difference among the three groups. One-way ANOVA and unpaired t-test were used to determine differences among and between groups and P<0.05 was considered significant. **P<0.01; ***P<0.001.