Table 1.
Baseline patient characteristics
| All patients (n=496) |
Patients with TB (n=81) |
Patients without TB (n=415) |
P-value | |
|---|---|---|---|---|
| Patient characteristics | ||||
| Age, median (IQR) | 33.6 (28.3-40.7) | 32.9 (28.5-39.3) | 33.6 (28.2-40.8) | 0.70 |
| Female | 317 (63.9) | 51 (63.0) | 266 (64.1) | 0.85 |
| BMI, median (IQR) | 23.4 (20.9-27.1) | 21.2 (19.3-26.0) | 23.8 (21.0-27.2) | <0.001 |
|
CD4 counts
(cells per μL)a |
||||
| Median (IQR) | 171 (98-233) | 138 (63-205) | 174 (111-238) | 0.004 |
| CD4 <50 | 62 (12.5) | 18 (22.2) | 44 (10.6) | |
| CD4 50-99 | 63 (12.7) | 11 (13.6) | 52 (12.6) | |
| CD4 100-149 | 90 (18.2) | 16 (19.8) | 74 (17.9) | 0.041 |
| CD4 150-199 | 96 (19.4) | 12 (14.8) | 84 (20.3) | |
| CD4 ≥200 | 184 (37.2) | 24 (29.6) | 160 (38.7) | |
|
Baseline viral load (log
copies per mL), median (IQR)b |
4.6 (4.1-5.0) | 4.8 (4.4-5.3) | 4.5 (4.0-5.0) | <0.001 |
| WHO stage at enrolment | ||||
| 1 or 2 | 334 (67.3) | 45 (55.6) | 289 (69.6) | 0.013 |
| 3 or 4 | 162 (32.7) | 36 (44.4) | 126 (30.4) | |
|
Previous history of
tuberculosis |
131 (26.4) | 16 (19.8) | 115 (27.7) | 0.14 |
|
Positive WHO symptom
screen |
344 (69.4) | 67 (82.7) | 277 (66.8) | 0.004 |
|
Current cough ≥ 2 weeks
Radiological |
102 (20.6) | 21 (25.9) | 81 (19.5) | 0.19 |
|
abnormality consistent
with tuberculosis c |
224 (49.7) | 58 (74.4) | 166 (44.5) | <0.001 |
a
CD4 cell counts available for 495 patients.
b
Viral load data available for 494 patients.
c
Chest radiographs were available for 451 patients