Table 1.
Baseline Characteristics of 52 Subjects With Postsurgical Hypoparathyroidism
| Mean ± SD (Median) | Normal Range | |
|---|---|---|
| Age, y | 48 ± 13 (48) | |
| Sex, n | ||
| Females | 45 | |
| Premenopausal | 28 | |
| Postmenopausal | 17 | |
| Males | 7 | |
| Caucasians, % | 98 | |
| Reason for neck surgery | ||
| Primary hyperparathyroidism | 7 | |
| Thyroid cancer | 23 | |
| Benign thyroid disease | 22 | |
| Duration of hypoparathyroidism, y | 11 ± 11 (6) | |
| Calcium supplement dose, g/d | 2.95 ± 2.1 (2.0) | |
| 1,25-Dihydroxyvitamin D supplement dose, μg/d | 0.81 ± 1.0 (0.50) | |
| Parent vitamin D dose (n = 32), IU/d | 10 842 ± 22 230 (1350) | |
| Hydrochlorothiazide dose (n = 10), mg/d | 34 ± 27 (25) | |
| Serum calcium, mg/dLa | 8.66 ± 0.9 (8.8) | 8.6–10.2 |
| Serum PTH, pg/mL | 3.0 ± 6 (undetectable) | 10–65 |
| Serum phosphate, mg/dL | 4.3 ± 0.8 (4.3) | 2.5–4.5 |
| Urinary calcium excretion, mg/d | 268 ± 130 (255) | 50–250b |
a
Serum calcium concentration was typically normal as a result of calcium and vitamin D supplementation.
b
For men, 50–300 mg/d.