Table 4.
Blood pressure control rates for each drug by plasma renin activity (PRA) and age criteria
Blood pressure control rate, % | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Black subjects | White subjects | |||||||||
Drug | All | PRA < 0.6 ng/ml/h | PRA ≥ 0.6 ng/ml/h | Aged < 50 y | Aged ≥ 50 y | All | PRA < 0.6 ng/ml/h | PRA ≥ 0.6 ng/ml/h | Aged < 50 y | Aged ≥ 50 y |
HCTZ | 55.2 | 57.9 | 52.7 | 43.2 | 47.2 | 52.4 | 49.2 | 53.8 | 49.7 | 55.9 |
Candesartan | 45.2*** | 36.9** | 70.5*** | 57.7**** | 51.4 | 78.1** | 63.7* | 89.6** | 77.2** | 78.7** |
Blood pressure control rate defined as percentage of subjects with BP <140/90mm Hg.
Abbreviation: HCTZ, hydrochlorothiazide.
*P = 0.006 candesartan vs. HCTZ.
**P < 0.001 candesartan vs. HCTZ.
***P = 0.02 candesartan vs. HCTZ.
****P = 0.01 candesartan vs. HCTZ.