Table 2.
Continuous blood pressure measures | ΔeGFRcys | |||||
---|---|---|---|---|---|---|
Full cohort | Stratified by hypertensive medication use at baseline | |||||
No (n = 2,371) | Yes (n = 1,994) | |||||
β (95% CI) | P value | β (95% CI) | P value | β (95% CI) | P value | |
Systolic blood pressure (per 10mm Hg)† | ||||||
Unadjusted | –0.15 (–0.20, –0.10) | <0.001 | –0.17 (–0.25, –0.08) | <0.001 | –0.15 (–0.20, –0.09) | <0.001 |
Demo adjusteda | –0.14 (–0.19, –0.09) | <0.001 | –0.16 (–0.24, –0.07) | 0.001 | –0.13 (–0.19, –0.08) | <0.001 |
Fully adjustedb | –0.13 (–0.19, –0.08) | <0.001 | –0.13 (–0.22, –0.04) | 0.004 | –0.13 (–0.19, –0.08) | <0.001 |
Diastolic blood pressure (per 10mm Hg)‡ | ||||||
Unadjusted | –0.09 (–0.19, 0.01) | 0.080 | –0.16 (–0.32, –0.004) | 0.045 | –0.01 (–0.12, 0.10) | 0.865 |
Demo adjusteda | –0.10 (–0.20, 0.03) | 0.056 | –0.18 (–0.34, –0.017) | 0.031 | –0.01 (–0.12, 0.10) | 0.801 |
Fully adjustedb | –0.10 (–0.20, 0.01) | 0.051 | –0.17 (–0.33, 0.001) | 0.051 | –0.03 (–0.14, 0.08) | 0.631 |
Pulse pressure (per 10mm Hg)§ | ||||||
Unadjusted | –0.17 (–0.23, –0.11) | <0.001 | –0.16 (–0.26, –0.06) | 0.002 | –0.19 (–0.25, –0.13) | <0.001 |
Demo adjusteda | –0.16 (–0.22, –0.10) | <0.001 | –0.15 (–0.25, –0.04) | 0.007 | –0.18 (–0.25, –0.12) | <0.001 |
Fully adjustedb | –0.15 (–0.21, –0.09) | <0.001 | –0.12 (–0.23, –0.01) | 0.029 | –0.18 (–0.24, –0.11) | <0.001 |
Abbreviation: CI, confidence interval.
aAdjusted for age, gender, race.
bAdjusted for age, gender, race, body mass index, smoking, diabetes mellitus, prevalent cardiovascular disease, low-density lipoprotein, and high-density lipoprotein .
†P value for interaction between systolic blood pressure and hypertensive medications = 0.802.
‡P value for interaction between diastolic blood pressure and hypertensive medications = 0.191.
§P value for interaction between pulse pressure and hypertensive medications = 0.419.