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. 1996 Oct 15;93(21):11956–11961. doi: 10.1073/pnas.93.21.11956

A model of multiplicative neural responses in parietal cortex.

E Salinas 1, L F Abbott 1
PMCID: PMC38165  PMID: 8876244

Abstract

Visual responses of neurons in parietal area 7a are modulated by a combined eye and head position signal in a multiplicative manner. Neurons with multiplicative responses can act as powerful computational elements in neural networks. In the case of parietal cortex, multiplicative gain modulation appears to play a crucial role in the transformation of object locations from retinal to body-centered coordinates. It has proven difficult to uncover single-neuron mechanisms that account for neuronal multiplication. Here we show that multiplicative responses can arise in a network model through population effects. Specifically, neurons in a recurrently connected network with excitatory connections between similarly tuned neurons and inhibitory connections between differently tuned neurons can perform a product operation on additive synaptic inputs. The results suggest that parietal responses may be based on this architecture.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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