. Author manuscript; available in PMC: 2013 Nov 4.

Published in final edited form as: Biol Blood Marrow Transplant. 2012 May 4;18(11):10.1016/j.bbmt.2012.04.016. doi: 10.1016/j.bbmt.2012.04.016

Table 3.

Proportional hazards modeling of risk of HHV-6-PALE after allogeneic HSCT

Characteristics	Univariable HR (95% CI)	P	Multivariable HR (95% CI)^****	P
UCBT	14.5 (5.9–35.8)	<0.0001	20.0 (7.3–55.0)	<0.0001
Male	1.61 (0.6–4.2)	0.34	—	—
Nonwhite	4.63 (1.4–15.9)	0.01	—	—
Myeloablative conditioning	1.60 (0.6–4.0)	0.31	—	—
Mismatched adult donor^††††	2.38 (0.7–8.2)	0.17	4.3 (1.1–17.3)	0.04
Unrelated adult donor	0.62 (0.3–1.5)	0.30	—	—
ATG	4.68 (1.8–11.9)	0.001	—	—
Acute GVHD: grades II–IV^‡‡‡‡	8.07 (3.08–21.2)	<0.0001	7.5 (2.8–19.8)	<0.0001

^****

Multivariable cox model analysis adjusting for UCBT, time-dependent acute GVHD grades II–IV, and mismatched donor.

^††††

To accurately calculate values for mismatched and unrelated donors, a dummy variable was made to separate the analysis into 3 groups (adult-donor HSCT mismatched or unrelated versus UCBT versus matched or unrelated HSCT) to avoid counting UCBT patients twice, given that all UCBT were mismatched-unrelated donors in this cohort.

^‡‡‡‡

Acute GVHD was modeled as a time-varying covariate.