Table 2.
Adipocytokines and RH-PAT score in lean control and obese adolescents with normal and impaired glucose tolerance test
| Adipocytokines |
Lean control (n = 14)
|
Obese
|
Obese total (n = 37) | P * | P ** for trend | |
|---|---|---|---|---|---|---|
| Obese NGT (n = 22) | Obese IGR (n = 15) | |||||
|
Adiponectin (μg/ml) |
7.53 ± 1.17 |
5.84 ± 0.51 |
5.17 ± 0.74 |
5.63 ± 0.42 |
0.09 |
0.10 |
|
Leptin (ng/ml) |
18.39 ± 4.49 |
34.28 ± 3.41 |
32.95 ± 4.67 |
33.77 ± 2.71 |
0.004 |
0.02 |
|
hsCRP (mg/l) |
0.69 ± 0.24 |
5.21 ± 1.11 |
4.16 ± 0.98 |
4.76 ± 0.76 |
0.0004 |
0.001 |
|
TNF-α (pg/ml) |
13.48 ± 1.03 |
20.07 ± 5.05 |
27.12 ± 6.69 |
22.94 ± 4.03 |
0.03 |
0.006 |
|
FFA (mmol) |
0.48 ± 0.06 |
0.60 ± 0.09 |
0.50 ± 0.04 |
0.55 ± 0.05 |
0.38 |
0.67 |
| RH-PAT score | 1.98 ± 0.09 | 1.73 ± 0.08 | 1.65 ± 0.12 | 1.70 ± 0.06 | 0.02 | 0.03 |
Legend -- CRP -- C-reactive protein, TNF-α—tumor necrosis factor, FFA- free fatty acids, RH-PAT -Peripheral arterial tonometry-hyperemic response. Values are mean ± SE, p*- lean vs. obese using independent t test, p**- p for trend using spearman correlation.