Table 2.
Incomplete excision of SCCs after surgical excision
| Study and No of excisions | Site | Proportion (95% CI) incompletely excised | Prognostic features* | Excision margin |
|---|---|---|---|---|
| Ang 2004 (n=63) | All | 0.16 (0.08 to 027) | Mean diameter 19.7 mm | Retrospective; 4-6 mm margin |
| Baker 2001 (n=227) | Head and neck | 0.07 (0.04 to 0.11) | No data | Retrospective; margin not specified |
| Bogdanov-Berezovsky 2005 (n=369) | All | 0.07 (0.04 to 0.10) | Completely excised: diameter 1.1 cm, depth 0.6 cm; differentiation: well (84.6%), moderate (13.6%), poor (5.6%). Incompletely excised: diameter 0.9 cm, depth 0.4 cm; differentiation: well (72.2%); moderate (22.2%); poor (5.6%) | Retrospective; 3-6 mm margin |
| Bovill 2009 (n=676) | All | 0.18 (0.15 to 0.21) | Re-excision cohort: mean diameter 17.2 mm, mean thickness 6.02mm; differentiation: well (43%), moderate (42%); poor (15%), perineural invasion (3.6%) | Retrospective; margin not specified |
| Griffiths 2002 (n=93) | All | 0.04 (0.01 to 0.11) | Median thickness 3.1 mm; mean diameter 13 mm (surviving patients) v 20 mm (patients who died of disease); immunocompromised (3.2%) | Retrospective; mean margin 7.2 mm (surviving patients) v 6.3 mm (patients who died of disease) |
| Mourouzis 2009 (n=218) | Head and neck | 0.12 (0.08 to 0.17) | Diameter <2 cm (63%), 2-4 cm (33.8%), >4 cm (3.2%); differentiation: well (78.2%), poor (21.8%); perineural invasion (2.3%), perivascular invasion (0.5%) | Retrospective; 5 mm margin |
| Nemet 2006 (n=68) | Periocular | 0.25 (0.15 to 0.37) | Differentiation: well (86.8%), moderate (13.2%) | Retrospective; 5 mm margin |
| Pua 2009 (n=69) | All | 0.00 (0.00 to 0.05) | Diameter <1 cm to 2 cm | Retrospective; 4 mm (“wider” for larger tumours) |
| Tan 2007 (n=480) | All | 0.06 (0.04 to 0.09) | Diameter <1 cm (52.3%), <2 cm (40.8%), >2 cm (33%) | Prospective; margin 2 mm to >10 mm |
| Thomas 1994 (n=54) | Pinna | 0.11 (0.04 to 0.23) | Stages I (52%), II (37%), III (0%), IV (11%); differentiation: well (68.5%), moderate (9.3%), poor (7.4%) | Retrospective; wedge excision to complex surgical procedure |
| Thomas 2003 (n=26) | All | 0.00 (0.00 to 0.13) | Average diameter 16.9 mm, diameter >10 mm (26%); differentiation: well (57.8%), moderate (38.5%), poor (3.8%) | Prospective; margin based on diagnosis and surgeon’s preference |
*Percentages indicate proportion of excisions in study.