Figure 3. MLN8237 induces polyploidy in Peripheral T-cell Lymphoma cell lines.
TIB-48 and CRL-2396 cells were treated with 0, 0.5, 1.0 and 1.5 μM of MLN8237 for 48 hr. Samples were harvested and stained with propidium iodide for DNA content analysis by flow cytometry. X-axis: DNA content, Y-axis: cell numbers.
