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. 2013 Jan 28;6(2):124–160. doi: 10.3390/ph6020124

Figure 2.

Figure 2

Strategies for siRNA screening process to identify new therapeutic target toward drug repurposing. Following primary and secondary screens, potential gene targets are further analyzed in silico using pathway analyses and database mining to determine desirable drug targets and available compounds. Efficacy and safety of these compounds can then be assessed in vitro and in vivo before clinical trials can be justified.