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. Author manuscript; available in PMC: 2013 Nov 4.
Published in final edited form as: Bioorg Med Chem. 2011 Feb 2;19(6):10.1016/j.bmc.2011.01.060. doi: 10.1016/j.bmc.2011.01.060

Table 2.

Inhibitory potencies of 9-amino analogs (8 and 9) for hCD22 and mCD22.

Compd. Activitya
mCD22 hCD22
IC50 (μM) rIPb IC50 (μM) rIP
2 6.43 ± 0.00 1 0.53 ± 0.00 1
8 5.03 ± 3.54 1.2 0.82 ± 0.02 0.6
9 23.33 ± 5.51 0.3 1.12 ± 0.06 0.5
a

Footnote of table 1.