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Representative examples of mean (solid), standard deviation (dotted) and maximum (dashed) temperatures over a 124 s sonication, analysed from the axial slices. The maximum temperature curve shows the measured maximum temperature within the heated region, while the mean temperature curve depicts the mean temperature with standard deviations within the predefined control point (5 voxels). Sonication was automatically stopped when the control point mean temperature reached 56 °C.
