Table 2.
|
HWEa |
|
|||||||
---|---|---|---|---|---|---|---|---|---|
|
Whole population |
White |
Pardo |
Black |
|
||||
SNP | χ2 | p | χ2 | p | χ2 | p | χ2 | p | Fst |
IκBL −62AT | 0.298 | 0.584 | 2.345 | 0.125 | 0.913 | 0.339 | 0.247 | 0.619 | 0.038 |
IκBL −262TC | 24.652 | ≤0.05 | 16.871 | ≤0.05 | 1.546 | 0.213 | 20.000 | ≤0.05 | 0.034 |
TNFa −238GA | 0.001 | 0.973 | 0.677 | 0.410 | 0.417 | 0.233 | 0.106 | 0.743 | 0.009 |
TNFa −308GA | 2.407 | 0.120 | 1.381 | 0.239 | 0.973 | 0.323 | 0.106 | 0.743 | 0.065 |
LTa +80AC | 15.296 | ≤0.05 | 9.024 | ≤0.05 | 6.428 | ≤0.05 | 0.960 | 0.327 | 0.008 |
LTa +252AG | 2.063 | 0.150 | 2.544 | 0.110 | 0.372 | 0.541 | 0.464 | 0.495 | <0.001 |
FAS −670AG | 0.554 | 0.456 | 0.659 | 0.416 | 2.164 | 0.141 | 2.666 | 0.102 | 0.031 |
FASL −844TC | 0.268 | 0.604 | 0.164 | 0.685 | 0.048 | 0.825 | 0.158 | 0.690 | 0.030 |
Equilibrium was assumed when p>0.05.
χ2, chi-square; p, significance value; Fst, genetic distance coefficient; HWE, Hardy–Weinberg equilibrium.