Table 3.
|
Population |
|
|
|
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
General |
White |
Pardo |
Black |
White vs. Pardo |
Pardo vs. Black |
Black vs. White |
||||
SNP genotype | No. | f | No. | f | No. | f | No. | f | p | p | p |
IκBL −62AT | |||||||||||
AA | 80 | 0.428 | 49 | 0.454 | 20 | 0.345 | 11 | 0.524 | 0.197 | 0.299 | 0.411 |
AT | 82 | 0.439 | 42 | 0.389 | 31 | 0.534 | 9 | 0.429 | |||
TT | 25 | 0.134 | 17 | 0.157 | 7 | 0.121 | 1 | 0.048 | |||
N/a | 65 | ||||||||||
IκBL −262TC | |||||||||||
TT | 126 | 0.783 | 75 | 0.806 | 33 | 0.688 | 18 | 0.900 | 0.191 | 0.046a | 0.217 |
TC | 24 | 0.149 | 12 | 0.129 | 12 | 0.250 | 0 | — | |||
CC | 11 | 0.068 | 6 | 0.065 | 3 | 0.063 | 2 | 0.100 | |||
N/a | 91 | ||||||||||
TNFa −238GA | |||||||||||
GG | 203 | 0.871 | 119 | 0.869 | 63 | 0.875 | 21 | 0.875 | 0.356 | 0.833 | 0.616 |
GA | 29 | 0.124 | 18 | 0.131 | 8 | 0.111 | 3 | 0.125 | |||
AA | 1 | 0.004 | 0 | — | 1 | 0.014 | 0 | — | |||
N/a | 19 | ||||||||||
TNFa −308GA | |||||||||||
GG | 190 | 0.815 | 112 | 0.818 | 57 | 0.792 | 21 | 0.875 | 0.651 | 0.280 | 0.362 |
GA | 43 | 0.185 | 25 | 0.182 | 15 | 0.208 | 3 | 0.125 | |||
AA | 0 | 0.000 | 0 | — | 0 | — | 0 | — | |||
N/a | 19 | ||||||||||
LTa +80AC | |||||||||||
AA | 14 | 0.106 | 9 | 0.123 | 2 | 0.057 | 3 | 0.125 | 0.520 | 0.586 | 0.668 |
AC | 87 | 0.659 | 49 | 0.671 | 24 | 0.686 | 14 | 0.583 | |||
CC | 31 | 0.235 | 15 | 0.205 | 9 | 0.257 | 7 | 0.292 | |||
N/a | 120 | ||||||||||
LTa +252AG | |||||||||||
AA | 104 | 0.491 | 68 | 0.548 | 29 | 0.460 | 7 | 0.280 | 0.257 | 0.231 | 0.006a |
AG | 95 | 0.448 | 52 | 0.419 | 29 | 0.460 | 14 | 0.560 | |||
GG | 13 | 0.061 | 4 | 0.032 | 5 | 0.079 | 4 | 0.160 | |||
N/a | 40 | ||||||||||
FAS −670AG | |||||||||||
AA | 44 | 0.208 | 29 | 0.236 | 10 | 0.159 | 5 | 0.192 | 0.473 | 0.041a | 0.016a |
AG | 111 | 0.524 | 66 | 0.537 | 37 | 0.587 | 8 | 0.308 | |||
GG | 57 | 0.269 | 28 | 0.228 | 16 | 0.254 | 13 | 0.500 | |||
N/a | 40 | ||||||||||
FASL −844TC | |||||||||||
TT | 50 | 0.236 | 28 | 0.228 | 12 | 0.190 | 10 | 0.385 | 0.781 | 0.048a | 0.096 |
TC | 102 | 0.481 | 59 | 0.480 | 30 | 0.476 | 13 | 0.500 | |||
CC | 60 | 0.283 | 36 | 0.293 | 21 | 0.333 | 3 | 0.115 | |||
N/a | 40 |
Significant genotypic differences.
N/a, not available, not included in statistical calculations; f, frequency; p, significance value.