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Detection of Cre-mediated deletion of exon 2 of the Men1 gene in tumors from Men1loxP/loxP/Rip-cre+ mice. Multiplex PCR products were run on a 3% agarose gel and stained with Vista Green, which revealed the presence of homozygous floxed Men1 exon 2 (FE2/FE2) and deleted exon 2 (DE2/DE2) alleles. Lanes: MW; molecular size markers (GIBCO-BRL 1-kb ladder); NORMAL, liver tissue; TUMOUR, pituitary adenoma.
