FIG. 4.

Lower splicing of dmpi8 in arrhythmic clock mutants. (A and B) Wild-type (CS) and clock mutant flies (per⁰ and tim⁰) were exposed to 4 days of 12:12LD at either 18°C (A) or 29°C (B). Comparisons of peak to trough values resulted in the following P values: per⁰¹ at 18 and 29°C, P < 0.01; tim⁰ at 18 and 29°C, P < 0.03. (C) In separate experiments, CS flies were kept at 29°C and collected on the last day of 12:12LD and the first day of DD. The data are derived from an average of two independent RT-PCR experiments.