Skip to main content
. Author manuscript; available in PMC: 2014 Mar 19.
Published in final edited form as: Nature. 2013 Sep 11;501(7467):380–384. doi: 10.1038/nature12530

Figure 2. Ts65Dn mice, but not Ts65Dn/Usp16het mice, show defective neuralprogenitor cells.

Figure 2

a, ELDA for SVZ Lin− cells (at P4). b,c, Nsp-IC frequency and Sox2 mRNA levels decrease only in Ts65Dn culture. d,e, ELDA and secondary sphere formation experiments with the indicated populations show an neural progenitor expansion deficit specific to Ts65Dn mice. (n=3 per group in all experiments).