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CYP2D6 star allele score definition.
| CYP2D6 Alleles | Function | System 1 (Zineh et al.) | System 2 (Zanger et al.) | Proposed Gene Score System |
|---|---|---|---|---|
| *3-*8, *11-*16, *18-*20, *36, *38, *40, *42, *44, *56, *4×N | PM | 0 | 0 | 0 |
| *10, *17, *37 | IM | 0.5 | 1 | 0.5 |
| *9, *29, *41, *45, *46 | IM | 0.75 | 1 | 0.5 |
| *1, *2, *33, *35 | EM | 1 | 2 | 1 |
| *41×N, *45×N | UM | 1.5 | 3 | 1 |
| *1×N, *2×N, *35×N | UM | 2 | 3 | 2 |
Note: proposed gene score system is similar to Gaedigk's system (34). The addition is assigning *41×N as 1.
