Table 1.

Yields of DNA damage (×10⁻⁸ damage/Gy/bp) for 10-KeV (a) and 10-eV (b) electron irradiation of DNA with and without modification by Pt-drugs.

Irradiation	DNA Damage*	Pure DNA	Cisplatin-DNA	Carboplatin-DNA	Oxaliplatin-DNA
10 KeV	SSB	145.3 ± 23.6	152.2 ± 26.5	160.4 ± 18.6	151.4 ± 18.9
	DSB	0.7 ± 0.1	0.9 ± 0.1	1.2 ± 0.1	1.2 ± 0.1
	CL	4.5 ± 0.6	6.8 ± 1.1	7.3 ± 0.3	7.1 ± 0.9
10 eV	SSB	78.7 ± 16.2	110.1 ± 15.8	120.4 ± 21.7	114.3 ± 26.3
	DSB	1.2 ± 0.2	3.0 ± 0.2	3.7 ± 0.2	2.9 ± 0.2
	CL	3.3 ± 0.9	7.2 ± 2.1	10.2 ± 1.6	13.5 ± 4.6

^*SSB: single strand break; DSB: double strand break; CL: interduplex cross-link