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. 2013 Nov 4;8(11):e79841. doi: 10.1371/journal.pone.0079841

Figure 4. Enhanced Nrf2 activity increases AMPKα phosphorylation in liver of Keap1-KD mice.

Figure 4

Immunoblot analysis of (A) Acc-1, Scd-1, and (B) total and p-AMPKα, total-AMPKβ1/2, and p-AMPKβ1 in livers of C57BL/6 (WT) and Keap1-KD (KD) mice. *, P<0.05, WT-Fasted compared with WT-Fed mice; #, P<0.05, KD-Fasted compared with KD-Fed mice; §, P<0.05, KD-Fasted compared with WT-Fasted mice. (C) p-AMPKα levels were increased in primary hepatocytes isolated from C57BL/6 (WT) and Keap1-KD (KD) mice. &, P<0.05, KD compared with WT mice hepatocytes.