Figure 2. Lesion morphology and size in the aortic sinus of 6 month old apoE-deficient mice.

Lesion morphology as shown in representative slices of aortic sinus stained by Masson’s trichrome in 6 month-old control apoE-KO (A) and SSR128129E-treated mice (B). Aortic sinus lesion size was determined by image analysis in 6 month-old apoE-deficient mice (C, n= 8 per group).