Figure 2. FLZ ameliorated learning and memory deficits of APP/PS1 mice.

APP/PS1 double transgenic mice were orally treated with FLZ 150 mg/kg for 20 weeks, and the learning and memory ability was accessed by passage water maze test. (A) The latencies of mice to find the destination. (B) Number of platform crossing. (C) Time in the target quadrant. (D) Travel distance. Results were expressed as mean±SD. *P<0.05,**P<0.01 vs, WT mice, ^# P<0.05 vs. APP/PS1 transgenic mice. n = 10 in each group.