Table 1. Baseline characteristics of study patients.
Characteristic | Ibuprofen group (n = 80) | Paracetamol group (n = 80) | P value |
Gestational age (week) | 30.9±2.2 | 31.2±1.8 | 0.474 |
Birth weight (g) | 1531.0±453.5 | 1591.9±348.6 g | 0.342 |
Gender | 0.874 | ||
Male | 42 | 41 | |
female | 38 | 39 | |
Cesarean birth, n (%) | 48(60%) | 52(65%) | 0.447 |
PIH, n (%) | 33(41.2%) | 34(42.5%) | 0.873 |
Antenatal glucocorticoid n (%) | 45(56.2%) | 47(58.8%) | 0.749 |
Perinatal asphyxia, n (%) | 10(12.5%) | 11(13.8%) | 0.815 |
Early-onset infection, n (%) | 11(13.8%) | 10(12.5%) | 0.815 |
Surfactant treatment, n (%) | 38(47.5%) | 39(48.8%) | 0.874 |
NCPAP, n (%) | 52(65.0%) | 58(72.5%) | 0.306 |
NSIMV, n (%) | 31(38.8%) | 29(36.2%) | 0.744 |
SIMV, n (%) | 10(12.5%) | 12(15.0%) | 0.646 |
IVH grade 1–2, n (%) | 11(13.8%) | 9(11.3%) | 0.633 |
Mean ductal diameter (mm) | 2.36±0.49 | 2.41±0.44 | 0.459 |
Mean max shunt velocity (mm/s) | 191.9±30.0 | 190.8±27.5 | 0.805 |
LA/Ao | 1.60±0.27 | 1.67±0.23 | 0.103 |
pregnancy induced hypertension syndrome(PIH).