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. 2013 Nov 4;8(11):e77888. doi: 10.1371/journal.pone.0077888

Table 2. Efficacy of paracetamol and ibuprofen treatments.

Paracetamol group (n = 80) Ibuprofen group (n = 80) P value
Overall closure rate, n (%) 65(81.2%) 63(78.8%) 0.693
Primary closure rate 45(56.3%) 38(47.5%) 0.268
Secondary closure rate 20 (25%) 25(31.3%) 0.379
Reopening after closure 5(7.7%) 6(9.5%) 0.712
Reclosure rate a 4 (80%) 4(66.7%) 0.621
Mean days needed for closure 3.22±0.14 3.71±0.16 0.020
a

Ductal closure rate after continuing drug treatment among infants with ductal reopening.