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. 2013 Nov 4;8(11):e77863. doi: 10.1371/journal.pone.0077863

Figure 9. Proposed model for NDL function in the meristem and inflorescence stems.

Figure 9

The connection between RGS1, GPA1 and AGB is based on data shown in this publication and previously published studies [83]–[86]. NDL1 and AGB1 are positive regulators of basipetal auxin transport (Fig 7A). They also function in auxin-regulated organ formation (Fig 1C and 3) and lateral meristem formation (Figs 2, 5, and 6) by establishing and/or maintaining auxin maxima (Fig 7B to I). Auxin positively regulates AGB1 expression, whereas it has a negative effect on NDL1 stability [40]. Furthermore, auxin increases strigolactone biosynthesis, which subsequently activates MAX2 via SLBPs [5]. Together, NDL1 and AGB1 regulate MAX2 expression (Fig. 8). The scheme does not illustrate the actions of the three NDL proteins. Genetic interactions are represented by straight arrows, biochemical interactions are represented by wavy arrows, and a proposed interaction is represented by a wavy hatched arrow.