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Corticosterone (CORT) increases AMPAR/NMDAR ratio of glutamatergic inputs to NAc shell medium spiny neurons (MSNs). Average AMPAR/NMDAR ratios in NAc shell MSNs measured in mice given 2 consecutive daily intraperitoneal injections of vehicle (50% DMSO, 50% saline), 10 mg/kg CORT, or 25 mg/kg CORT. The AMPAR/NMDAR ratios from animals receiving the 10 mg/kg CORT were increased compared with control and 25 mg/kg CORT-treated mice (*P < 0.003, #P < 0.035).
