Table 3. Associations between socioeconomic factors and mortality from all causes with inclusion of the potential mediators (comorbidity and cancer stage), among 1961 Danish women with cervical cancer diagnosed 2005–2010, and with inclusion of smoking for a subgroup of 1696 women.
| Model 1 Adjustment for age HR (95% CI) | Model 2 Adjusted HR (95% CI)a | Model 3 Adjustedb+comorbidity HR (95% CI) | Model 4 Adjustedc+cancer stage HR (95% CI) | Subgroup results Adjusted +smoking statusd HR (95% CI) | |
|---|---|---|---|---|---|
|
Level of education (n=1914) |
|
|
|
|
(n=1696) |
| Higher | 1 | 1 | 1 | 1 | 1 |
| Medium | 1.19 (0.92–1.54) | 1.19 (0.92–1.54) | 1.20 (0.89–1.62) | 1.03 (0.78–1.35) | 0.91 (0.62-1.33) |
| Short |
1.46 (1.20–1.77) |
1.46 (1.20–1.77) |
1.44 (1.19–1.75) |
1.07 (0.96–1.19) |
0.89 (0.75–1.05) |
|
Cohabitation status (n=1961) |
|
|
|
|
(n=1696) |
| All | |||||
| Married or cohabiting | 1 | 1 | 1 | 1 | 1 |
| Single, widowed, divorced |
1.11 (1.00-1.23) |
1.08 (0.97–1.20) |
1.01 (0.89–1.14) |
0.97 (0.87–1.09) |
1.02 (0.90-1.16) |
| Age<60 | |||||
| Married or cohabiting | 1 | 1 | 1 | 1 | 1 |
| Single, widowed, divorced |
1.58 (1.26–1.98) |
1.60 (1.29–1.98) |
1.59 (1.28–1.98) |
1.42 (1.16–1.74) |
1.24 (1.01–1.52) |
|
Disposable income (n=1881) |
|
|
|
|
(n=1634) |
| All | |||||
| Highest (4th quartile) | 1 | 1 | 1 | 1 | 1 |
| Middle (2nd–3rd quartile) | 1.15 (1.02–1.31) | 1.09 (0.94–1.25) | 1.08 (0.97–1.20) | 0.99 (0.87–1.12) | 0.90 (0.72–1.11) |
| Lowest (1st quartile) |
1.44 (1.17–1.76) |
1.32 (1.07–1.63) |
1.34 (1.12–1.62) |
1.15 (0.86–1.52) |
0.95 (0.74–1.21) |
| Age<60 | |||||
| Highest (4th quartile) | 1 | 1 | 1 | 1 | 1 |
| Lowest (1st quartile) | 1.90 (1.45–2.51) | 1.59 (1.29–1.95) | 1.56 (1.22–1.97) | 1.08 (0.86–1.35) | 0.80 (0.64–1.00) |
Abbreviations: CI=confidence interval; HR=hazard ratio; FIGO=Fédération Internationale des Gynécologistes et Obstetristes.
a
Education adjusted for age; cohabitation status adjusted for age and education; income adjusted for age, education and cohabitation status.
b
Adjustments as in model 2 and additionally adjusted for Charlson comorbidity index.
c
Adjustments as in model 3 and additionally adjusted for cancer stage (FIGO).
d
Subgroup results including patients with information on smoking registered, results adjusted for smoking status, comorbidity and cancer stage (FIGO).