Table 2.
Percentage Difference in Average C-reactive Protein and Interleukin-6 (Assessed in 1997/1999 and 2002/2004) Per 1-Hour Change in Duration of Sleep Between 1991/1994 and 1997/1999 Using Data From the Whitehall II Study
| Decreased Sleep |
Increased Sleep |
|||||
|---|---|---|---|---|---|---|
| Difference Per Hour, % | 95% CI | P Value | Difference Per Hour, % | 95% CI | P Value | |
| Model 1a | ||||||
| C-reactive proteinb | 8.1 | 2.6, 13.9 | 0.004 | −3.6 | −11.7, 5.3 | 0.42 |
| Interleukin-6c | 4.5 | 1.7, 7.4 | 0.001 | −1.4 | −5.7, 3.1 | 0.54 |
| Model 2d | ||||||
| C-reactive protein | 6.7 | 1.3, 12.5 | 0.01 | −3.5 | −11.5, 5.3 | 0.43 |
| Interleukin-6 | 3.6 | 0.8, 6.4 | 0.01 | −1.4 | −5.7, 3.1 | 0.53 |
| Model 3e | ||||||
| C-reactive protein | 4.2 | −0.9, 9.4 | 0.11 | −2.4 | −10.1, 5.9 | 0.56 |
| Interleukin-6 | 2.7 | 0.1, 5.3 | 0.04 | −0.7 | −4.8, 3.6 | 0.56 |
Abbreviation: CI, confidence interval.
a Model 1 is adjusted for age and sex.
b The numbers of participants with decreased hours, same hours, and increased hours of sleep between 1991/1994 and 1997/1999 are 1,757, 2,286, and 592, respectively.
c The numbers of participants with decreased hours, same hours, and increased hours of sleep between 1991/1994 and 1997/1999 are 1,657, 2,162, and 561, respectively.
d Model 2 is adjusted for age, sex, and occupational position in 1997/1999.
e Model 3 is adjusted for age, sex, occupational position, systolic blood pressure, body mass index, cholesterol concentration, and diabetes in 1997/1999.