Table 1.
Name | Label | Structure | Heterocycle | Scheme |
Nicotinic acid | 1.12 | pyridine | 2,3 | |
Niacin | 1.18 | pyridine | 3 | |
Clarinex | 1.22 | pyridine | 5 | |
Rabeprazole | 1.33 | pyridine | 6,7 | |
Pantoprazole | 1.34 | pyridine | 6,7 | |
Lansoprazole | 1.35 | pyridine | 6,7 | |
Rosiglitazone | 1.40 | pyridine | 8,11 | |
Pioglitazone | 1.41 | pyridine | 12–16 | |
Etoricoxib | 1.90 | pyridine | 17,18 | |
Moxifloxacin | 1.102 | quinolone | 19,20 | |
Levofloxacin | 1.103 | quinolone | 21,22 | |
Nifedipine | 2.1 | dihydropyridine | 23 | |
Amlodipine | 2.2 | dihydropyridine | 24,25 | |
Clevidipine | 2.3 | dihydropyridine | 26 | |
Tiagabine | 2.36 | piperidine | 27 | |
Solifenacin | 2.57 | piperidine | 28 | |
Carmegliptine | 2.70 | piperidine | 30 | |
Lamivudine | 3.1 | pyrimidine | 33 | |
Raltegravir | 3.18 | pyrimidine | 34 | |
Imatinib | 3.36 | pyrimidine | 37,38 | |
Erlotinib | 3.37 | pyrimidine | 39,40 | |
Lapatinib | 3.38 | pyrimidine | 41 | |
Rosuvastatin | 3.80 | pyrimidine | 42,43 | |
Varenicline | 4.1 | pyrazine | 44 | |
Eszopiclone | 4.26 | pyrazine | 45 | |
Brimonidine | 4.22 | pyrazine | 45 | |
Bortezomib | 4.27 | pyrazine | 46 | |
Aplaviroc | 4.37 | piperazine | 47 | |
Azelastine | 5.1 | pyridazine | 48 | |
Cilazapril | 5.12 | perhydro-pyridazine | 49 | |
Lamotrigine | 6.1 | 1,2,4-triazine | 50,51 | |
Imiquimod | 6.11 | imidazoquinoline | 52–54 | |
Abacavir | 6.37 | purine | 55 | |
Ocinaplon | 6.48 | pyrazolo-pyrimidine | 56 | |
Zaleplon | 6.46 | pyrazolo-pyrimidine | 57 | |
Indiplon | 6.54 | pyrazolo-pyrimidine | 57 | |
Sildenafil | 6.61 | pyrazolo-pyrimidone | 58–61 | |
Vardenafil | 6.87 | imidazotriazinone | 62–65 | |
Temozolomide | 6.105 | imidazo-tetrazinone | 66–68 |