Table 1.

Schedules of Conditioning Regimens and Antiemetics

Regimens	Dosage and Administrationa
TBI/CY
TBIa	2 Gy, twice/day	Days −6, −5, −4
Cyclophosphamide	60 mg/kg, once/day	Days −3, −2
Granisetron	3 mg, twice/day	Days −6 to −2
Aprepitantb	Once/day	125 mg on day −3; 80 mg on days −2, −1
BU/CY
Busulfan	0.8 mg/kg, every 6 hrs	Days −7 to −4
Cyclophosphamide	60 mg/kg, once/day	Days −3, −2
Granisetron	3 mg, twice/day	Days −7 to −2
Aprepitantb	Once/day	125 mg on day −7; 80 mg on days −6 to −2
Flu/BU4
Fludarabine	30 mg/m2, once/day	Days −8 to −3
Busulfan	0.8 mg/kg, every 6 hrs	Days −6 to −3
TBI (for UR donor)	2 Gy, once/day	Day −1
Granisetron	3 mg, twice/day	Days −8 to −3, −1
Aprepitantb	Once/day	125 mg on day −6; 80 mg on days −5 to −3
Flu/BU2
Fludarabine	30 mg/m2, once/day	Days −8 to −3
Busulfan	0.8 mg/kg, every 6 hrs	Days −6, −5
TBI (for UR donor)	2 Gy, once/day	Day −1
Granisetron	3 mg, twice/day	Days −8 to −3, −1
Aprepitantb	Once/day	125 mg on day −6; 80 mg on days −5, −4
Flu/CY
Fludarabine	25 mg/m2, once/day	Days −5 to −1
Cyclophosphamide	30–60 mg/kg, once/day	Days −7, −6
Granisetron	3 mg, twice/day	Days −7 to −1
Aprepitantb	Once/day	125 mg on day −7; 80 mg on days −6, −5
Flu/MEL/TBI
Fludarabine	25 mg/m2, once/day	Days −8 to −4
Melphalan	40 mg/m2, once/day	Days −3, −2
TBI	2 Gy, once or twice/day	Day −1
Granisetron	3 mg, twice/day	Days −8 to −1
Aprepitantb	Once/day	125 mg on day −3; 80 mg on days −2, −1

TBI = total body irradiation; CY = cyclophosphamide; BU = busulfan; UR = unrelated donor; Flu = fludarabine; MEL = melphalan.

^aHematopoietic stem cell transplantation (HSCT) was performed on day 0.

^bPatients in the control group did not receive aprepitant.