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Experimental results for the cycloaddition of 1 with 4.
| Entry | Reactor | Time [min] | Conversion [%]a |
| 1 | Batch | 90 | 17 |
| 2 | 480 | 99 (30b) | |
| 3 | μ-Reactor | 7.5 | 16 |
| 4 | 15 | 25 | |
| 5 | 30 | 50 | |
| 6 | 30 | 53 | |
| 7 | 60 | 88 | |
| 8 | 60 | 90 (41b/46c) | |
| 9 | 90 | 97 (43b/44c) | |
aDetermined by 1H NMR analysis of the crude product (±2%). bIsolated yield after column chromatography. cIsolated yield based on conversion.
