Figure 2.
Pathogen-specific effector subset development from CD8+ T cell clones. a. Stacked graphs of the phenotypes of the progeny of 20 individual OVA-specific clones observed from one VSV-OVA experiment (20 mice, 40 possible clones). This experiment was repeated 4 times, with 80 mice total. b. Stacked graphs of the progeny of 17 individual OVA-specific clones from one LM-OVA experiment (20 mice, 40 possible clones). This experiment was repeated 3 times, with 60 mice total. c. 9 examples of distinct phenotypes of donor populations after VSV-OVA infection. Clones were classified as MPEC phenotype (2-fold greater MPEC than SLEC), SLEC phenotype (2-fold greater SLEC than MPEC), or MIXED. See also Figure S2.
