Table 1.
Metformin (µmol/L) | Carboplatin (µmol/L) | CI for A2780 Cell Line | CI for SKOV3 Cell Line |
---|---|---|---|
0.02 | 0.05 | 0.040 | 0.093 |
0.2 | 0.5 | 24.461 | 0.319 |
2 | 5 | 0.214 | 0.387 |
20 | 50 | 0.411 | 0.274 |
40 | 100 | 0.264 | 0.023 |
400 | 1000 | 0.061 | 0.007 |
a Combination index (CI) values obtained for A2780 and SKOV3 cell lines from Figure 5A. CI < 1 indicates synergy between the 2 drugs.