Table 3. Fragments generated by SCEDS as shown in Fig. 2 ▶ .

MR succeeded in cases (c)–(j). For adenylate kinase cases (a) and (b) the SCEDS fragments listed as most closely resembling the CORE, LID and NMP-binding (NMP) domains (Blaszczyk et al., 2001 ▶) are listed although MR with these failed.

	PDB code	Modes	NDOM	Fragment 1	Fragment 2	Fragment 3	Fragment 4	Fragment 5	Excluded
(a) Adenylate kinase, closed	2eck, chain B	7, 9	3	1–35, 68–124, 155–214 (CORE)	36–67 (NMP)	125–154 (LID)	—	—	None
(b) Adenylate kinase, open	4ake, chain A	7, 8	3	1–34, 68–117, 164–214 (CORE)	118–163 (LID)	35–67 (NMP)	—	—	None
(c) Calmodulin, closed	1ctr	9, 10	2	9–83	84–147	—	—	—	4–8
(d) Calmodulin, open	1cll	9, 10	2	12–72	88–147	—	—	—	1–11, 73–73, 81–87
(e) cAMP-dependent protein kinase	1atp, chain E	7, 8	2	15–35, 125–328	36–124, 222–350	—	—	—	329–332
(f) Citrate synthase	5csc, chain A	7, 8	2	1–82, 84–276, 385–433	277–291, 295–384	—	—	—	None
(g) Glutamine-binding protein	1ggg, chain A	8	2	5–82, 189–224	89–183	—	—	—	83–88, 184–188
(h) Maltodextrin-binding protein	1anf	7, 9	2	113–258, 319–370	8–112, 259–303	—	—	—	1–7
(i) Pyruvate phosphate dikinase	1kbl	11	4	566–828	6–243	244–380, 515–565, 829–873	381–514	—	2–5
(j) Pyruvate phosphate dikinase, triple mutant	2r82	7, 10	5	6–242	709–873	539–699	379–515	243–338	2–5, 340–370, 516–538, 700–708