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. 2013 Aug 21;6(8):1055–1081. doi: 10.3390/ph6081055

Figure 6.

Figure 6

Protease-activated AMP (Table 1). The peptide is composed of three domains: an AMP, a protective peptide, and a specific linker. The antimicrobial activity of the AMP is inhibited by conjunction with the anionic protective peptide. Virulent proteases cleave the specific linker and release the AMP, leading to its activation.