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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Jul 11;33(9):10.1161/ATVBAHA.113.301894. doi: 10.1161/ATVBAHA.113.301894

Figure 6.

Figure 6

CyPA PPIase activity is required for CyPA and p47phox interaction. A and B, RASMC were pretreated with PPIase inhibitor cyclosporin A (CsA 1μmol/L) for 1 hour and stimulated with AngII (10−7 mol/L) for 10 minutes and followed by immunoprecipitation and Western analysis to detect CyPA and p47phox or actin interaction. C and D, CyPA-Wild type (WT) or PPIase mutant (R55A) lentiviral particles were transduced into RASMC and immunoprecipitation and Western analysis were performed. Data are from three separate experiments and show mean±SEM. *P<0.05 vs 0 minute; #P<0.05 vs AngII.