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. Author manuscript; available in PMC: 2013 Nov 5.
Published in final edited form as: Mol Pharm. 2010 Nov 24;8(1):10.1021/mp1002653. doi: 10.1021/mp1002653

Figure 3. Nanoparticle Characterization.

Figure 3

Scanning electron micrographs of Non-targeted polymer blend nanoparticles (A) and targeted polymer blend nanoparticles (B). Scale bar is 1 μM. The targeting construct (C) is incorporated in the targeted nanocarriers so that the PLGA portion interacts with the PCL core while the PEG and EGFR-peptide protrude from the surface of the particle. ESCA analysis of the surface of the nanocarriers (D) confirmed the presence of the EGFR peptide (nitrogen) on the surface of the targeted nanoparticles while there was no detectable (n/d) nitrogen on the non-targeted nanoparticles.

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