Table 7: Sensitivity Analysis—Decreasing the sensitivity of the 13C UBT to 90.1%.
Total | Incremental | ||||
---|---|---|---|---|---|
Strategy | Cost ($)/Test | Misdiagnoses (FP +FN) | Cost ($)/Test | Misdiagnoses (FP +FN) Avoided | ICER $/Misdiagnoses Avoided |
ELISA serology | $13.96 | 0.2236 | Reference | Reference | Reference |
13C UBTa | $74.96 | 0.0888 | $61.00 | 0.1348 | $452 |
ELISA serology + 13C UBT | $50.02 | 0.0662 | $36.06 | 0.1574 | $229 |
Abbreviations: 13C UBT, carbon-13 urea breath test; ELISA, enzyme-linked immunosorbent assay; FN, false-negative result; FP, false-positive result: ICER, incremental cost-effectiveness ratio.
13C UBT dominated by ELISA serology + 13C UBT (13C UBT more costly, fewer misdiagnoses avoided than ELISA + 13C UBT).