Figure 2.

Collagen nanomorphology in connection to micro-scale bone lamellar structure. (a) A schematic of bone micro-architecture, showing lamellae with collagen fibril bundles at different orientations. (b) AFM error images showing two layers of collagen bundles presumably from two lamellae, and different D-spacing values are associated with the two bundles. (c) Three-dimentional bar plot showing that bundle D-spacings occupy the full spectrum of distribution ranging from 57 to 69 nm, whereas fibril D-spacings within one bundle are narrow (±1 nm). (a–c) are adapted from Fang et al.10