Table 1. Description of joint lesions in OA models.

Models	Structures involved	Cartilage destruction	Osteophyte formation
Severe	Patellar ligament	2 weeks	4 weeks
	Medial collateral ligament
	Medial meniscus
	Anterior cruciate ligament
	Posteror cruciate ligament
	Lateral meniscus
	Lateral collateral meniscus
Medial	Medial collateral ligament	8 weeks	12 weeks
	Medial meniscus
Moderate	Medial meniscus	4 weeks	4 weeks
	Anterior cruciate ligament
Mild	Anterior cruciate ligament	8 weeks	8 weeks