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. 2013 Oct 22;3(10):e318. doi: 10.1038/tp.2013.90

Table 1. Clock gene SNPs and MAF in BD cases and controls.

Gene SNP MAF Cont MAF BD Notes
BMAL1 rs2279287 31.6 13.2 Assoc BD, AKA ARNTL38
CLOCK rs1801260 31.6 26.3 Assoc BD and insomnia32
CRY1 rs8192440 26.3 28.9 Assoc Li response18
CRY2 rs2037311 2.6 2.6  
CSNK1E rs1534891 13.2 10.5  
GSK3β rs334558 28.9 28.9 Assoc Li response13, 14
NPAS2 rs11541353 18.4 23.7 Assoc SAD, AKA S471L33
Rev-Erbα rs2071427 18.4 18.4 Assoc Li response,18 AKA NR1D1
PER1 rs3027178 15.8 26.3  
PER2 rs56013859 15.8 26.3 Assoc SAD,33 AKA 10870
PER3 rs228729 36.8 26.3 Assoc BD,38 tags VNTR
RORA rs12912233 44.7 39.5 Assoc depression31

Abbreviations: Assoc, associated; AKA, also known as; MAF, minor allele frequency; SAD, seasonal affective disorder; SNP, single-nucleotide polymorphism; VNTR, variable number tandem repeat.

In some instances, past illness associations and reference are indicated. Also known as (AKA) indicates alternate name for SNP or gene.