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. 2013 Nov 1;8:4197–4213. doi: 10.2147/IJN.S50685

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© 2013 Xia et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Histological evaluation of new bone formation promoted by pure PCL and 15% nano-HA/PCL scaffolds (20× and 100× magnification).

Notes: Explanted bones were embedded in polymethylmethacrylate and processed for Van Gieson’s staining. Bone defects with implantation of (A-1 and A-2) pure PCL and (B-1 and B-2) PCL with 15 wt% nano-HA scaffolds at 3 weeks. Bone defects with implantation of (C-1 and C-2) pure PCL and (D-1 and D-2) PCL with 15 wt% nano-HA scaffolds at 9 weeks. White arrows: newly formed bone along the degrading material.

Abbreviations: HA, hydroxyapatite; MT, bone marrow tissue; NB, new bone; nHP-S, PCL with 15 wt% nano-HA scaffolds; PCL, poly-ε-caprolactone; P-S, pure PCL scaffolds.